1. Drake: Lil Wayne in Drake imata dolgo zgodovino sodelovanja, vključno s pesmimi, kot so "The Motto" (2011), "HYFR" (2011), "Right Above It" (2011), "Believe Me" (2011), "I'm on One" (2011), "She Will" (2011), "Grindin" (2011), "Pistol On My Side" (2011), "Up All Night" (2011) in "HYFR (Remix)" (2012) ).
2. Kanye West: Lil Wayne in Kanye West sta sodelovala pri pesmih, kot so "Mercy" (2012), "New God Flow" (2012), "Awesome" (2013), "RoboCop" (2013) in "Barry Bonds" (2013).
3. Eminem: Lil Wayne in Eminem sta sodelovala pri pesmih, kot so "No Love" (2010), "Drop the World" (2010) in "Forever" (2010).
4. Nicki Minaj: Lil Wayne in Nicki Minaj sta sodelovala pri številnih pesmih, vključno z "Knockout" (2009), "What Do You Mean" (2009), "Make Me Proud" (2011), "Beauty and a Beat" (2012), "Senile" (2012) in "Rimljani Revenge" (2012).
5. Jay-Z: Lil Wayne in Jay-Z sta sodelovala pri pesmih, kot so "Mr. Carter" (2011), "Can't Get Enough" (2011), "Talk About Our Love" (2011), "Money on my mind" (2011). , in "Blue Magic" (2011).
To je le nekaj primerov številnih sodelovanj, ki jih je Lil Wayne v svoji karieri sklenil z drugimi pomembnimi raperji.